Sentinel brain protection system to reduce cardiovascular stroke

Release date: 2017-06-08

Many heart valve repairs do not require large-scale open heart surgery. Transcatheter aortic valve repair (TAVR) is now a more common method, which is a less invasive option for many patients with weak body.

TAVR also faces certain risks during the operation. During the operation, the embolic fragments will be released. These fragments will pose serious risks to many tissues and organs of the body, especially the brain. These fragments will block the blood vessels in the blood. If it occurs in the brain, it will cause a stroke. .

Is there a way to prevent the fragments produced during surgery from entering the external circulatory system during surgery?

The FDA recently approved a sentinel brain protection system to prevent the risk of stroke in this TAVR procedure. This system comes from Claret Medical.

Schematic diagram of the process of implanting the sentinel system. (Source: Claret Medical)

The sentinel system is a percutaneous device that contains two filters that are delivered to the target location in a very subtle way, one of which is the brachiocephalic artery and the other is the left common carotid artery. The device was inserted from the right arm right iliac artery and placed at the junction of the brachiocephalic artery and the left common carotid artery. Dangerous debris will be trapped by the filter of the device, after which the captured debris will be removed from the right arm along with the device.

This sentinel system can be used in any procedure during TAVR, regardless of whether the valve is being implanted or not, and does not interfere with the procedure.

The large embolic particles were taken out after TAVR. (Source: Claret Medical)

The sentinel system is very fast, and it takes about 4 minutes to arrange two filters. In clinical studies, deployment success rates are as high as 99%. It can effectively collect debris, valve tissue, calcification, blood clots or other substances released during surgery to prevent them from entering the brain, greatly reducing the risk of stroke in patients.

Sentinel systems are also being studied in other intravascular procedures, such as intrathoracic repair (TEVAR), left atrial appendage (LAAO), and transcatheter mitral valve repair and replacement.

The extracorporeal control part of the sentinel system. (Source: Claret Medical)

Although the device is now only used for TAVR, for other minimally invasive and endovascular procedures, the sentinel system has a good application potential, allowing doctors to better focus on the surgery itself, and to ensure safe operation and postoperative safety. convoy.

Source: Health New Vision (Micro Signal HealthHorizon)

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