Factory Direct Antibotic Dalbavancin (CAS: 171500-79-1)

October 25, 2018

Model NO.: PHARMACEUTICAL GRADE
Origion: Hubei, China
Market: Global
Trademark: NEWBIO PHARMTECH
Transport Package: Aluminum Foil Bags or Fiber Drum
Specification: SGS
Origin: Wuhan, Hubei, China
HS Code: 0000000000
Model NO.: PHARMACEUTICAL GRADE
Origion: Hubei, China
Market: Global
Trademark: NEWBIO PHARMTECH
Transport Package: Aluminum Foil Bags or Fiber Drum
Specification: SGS
Origin: Wuhan, Hubei, China
HS Code: 0000000000
Factory Direct Antibotic Dalbavancin with High Purity
(CAS: 171500-79-1)
 
=====================================
Chemical Information:
Quick Details: 
Product name Dalbavancin
CAS NO. 171500-79-1
Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Standard purity:>99%
Appearance Dalbavancin powder
Shelf life 2 years
Usage Dalbavancin is a novel second-generation lipoglycopeptide antibiotic.
Storage Dalbavancin should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

Product Name: Dalbavancin
Model No.: CYN-271
CAS No.: 171500-79-1
Molecular Formula: C88h100cl2n10o28
Molecular Weight: 1816.69
Appearance: White Crystalline powder
Melting Point: N/A
COA: Available
MSDS: Available
Spectrum: Available
Purity: 99%+
Suitable People: ALL People
Product Specifications: Pharmaceutical Grade 
Standard: Qualified
MOQ(Minimum Order Quantity): 10g
Payment: L/C, T/T, Western Union
Shipment: EMS, DHL, FedEx
Packing: Aluminium Foil Bag or as Required    

 
=====================================
Product Description:
Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).
Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.
Puhopharma specializes in controling the quality and reducing the impurities of Dalbavancin.
Our Dalbavancin is with the best quality and the most competitive price in China.
Dalbavancin (INN, trade names Dalvance in the US and Xydalba in Europe) is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).
Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.
It possesses in vitro activity against a variety of Gram-positive pathogens including MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE).
It is a once-weekly, two-dose antibiotic, the rights to which Actavis acquired when it bought Durata Therapeutics in 2014.
The Food and Drug Administration approved dalbavancin in May 2014 for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by certain susceptible bacteria such as Staphylococcus aureus including methicillin-susceptible and methicillin-resistant strains of Streptococcus pyogenes, in intravenous dosage form.
 
===================================== 
Applications/Usage:
Dalbavancin is an antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) in adults caused by susceptible Gram-positive organisms, including methicillin-resistant Staphylococcus aureus(MRSA).
It has strong activity against many Gram-positive bacteria, including methicillin-sensitive and methicillin-resistant Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus anginosus,Streptococcus intermedius, and Streptococcus constellatus.
Dalbavancin is a semi-synthetic glycopeptide prepared from A40926 by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram positive and multi-drug resistant isolates such as MRSA and MRSE.
 
===================================== 
Drug Interaction:
Clinical drug-drug interactions with dalbavancin have not been studied, and dalbavancin does not appear to interact with cytochrome P450 substrates, inhibitors, or inducers. It was found to have an in vitro synergistic interaction with the antimicrobial oxacillin, but the clinical significance of this interaction has yet to be established.
 
===================================== 
Mechanism of Action:
Dalbavancin is a lipoglycopeptide belonging in the same glycopeptide class. Similar to other glycopeptides, dalbavancin exerts its bactericidal effect by disrupting cell wall biosynthesis. It binds to the D-alanyl-D-alanyl residue on growing peptidoglycan chains and prevents transpeptidation from occurring, preventing peptidoglycan elongation and cell wall formation. Dalbavancin also dimerizes and anchors itself in the lipophilic bacterial membrane, thereby increasing its stability in the target environment and its affinity for peptidoglycan.
Antimicrobial activity correlates with the ratio of area under the concentration-time curve to minimum inhibitory concentration for Staphylococcus aureus.
 
===================================== 
Side Effects:
The most common adverse reactions encountered in Phase II and Phase III trials were nausea (5.5%), headache (4.7%), and diarrhea (4.4%), as well as rash (2.7%) and itchiness (2.1%).

===================================== 
COA:
Items Standard
Description White or almost white, crystalline powder
Water ≤0.5%
Residue on ignition ≤0.1
Limit of chloride NMT0.03%
Heavy metals NMT0.001%
Methanol NMT0.1%
Alcohol NMT0.1%
Related components A NMT0.5%
Any unknown impurity NMT0.10%
Total impurities NMT2.0%
Assay 98.0%~102.0%


FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
S# CAS No. Product Name S# CAS No. Product Name
1  86639-52-3 7-Ethyl-10-Hydroxycamptothecin 25  183321-74-6 Erlotinib
2  154229-18-2 Abiraterone Acetate 26  183319-69-9 Erlotinib Hydrochloride
3  50-76-0 Actinomycin D 27  159351-69-6 Everolimus
4  106941-25-7 Adefovir 28  56296-78-7 Fluoxetine Hydrochloride
5  850140-72-6 Afatinib 29  184475-55-6 Gefitinib Hydrochloride
6  330784-47-9 Avanafil 30  136572-09-3 Irinotecan Hydrochloride 
TriHydrate
7  319460-85-0 Axitinib 31  1441674-54-9 Ledipasvir(Acetone)
8  1421373-66-1 AZD-9291 (Mesylate) 32  191732-72-6 Lenalidomide
9  123524-52-7 Azelnidipine 33  21672  Methotrexate
10  863031-21-4 Azilsartan Medoxomil 34  76144-81-5 Mildronate
11  179324-69-7 Bortezomib 35  474645-27-7 Monomethyl Auristatin E
12  357336-20-0 Brivaracetam 36  63121-00-6 Oxaliplatin
13  842133-18-0 Canagliflozin 49  33069-62-4 Paclitaxel
14  928672-86-0 Canagliflozin HemiHydrate 37  137281-23-3 Pemetrexed Disodium
15  41575-94-4 Carboplatin 38  53123-88-9 Rapamycin
16  50935-04-1 Carubicin 50  135062-02-1 Repaglinide
17  288383-20-0 Cediranib 39  945667-22-1 Saxagliptin Hydrate
18  15663-27-1 Cisplatin 40  709031-78-7 Saxagliptin Hydrochloride
19  877399-52-5 Crizotinib 41  486460-32-6 Sitagliptin
20  171500-79-1 Dalbavancin 42  654671-77-9 Sitagliptin Phosphate Hydrate
21  114977-28-5 Docetaxel 44  85622-93-1 Temozolomide
22  148408-66-6 Docetaxel TriHydrate 45  477600-75-2 Tofacitinib
23  25316-40-9 Doxorubicin hydrochloride 46  540737-29-9 Tofacitinib Citrate
24  133040-01-4 Eprosartan 47  170791-09-0 Trityl Candesartan Cilexetil

ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment. 
#2 Secure and discreet shipment. 
#3 Various methods for your choice, like DHL/FedEx/SF-express.

OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3  We have QA&QC department to guarantees the quality, product pass rate can reach 100%. 

CONTACT US:
Telephone +86-027-87002705
Mobile +86-13277093700
Skype newbiopharmtech
FaceBook Page https://www.facebook.com/newbiopharma/
Facebook Group https://www.facebook.com/groups/1739616069613416/
Website http://www.newbiopharm.com/
Online Store http://biocar.en.made-in-china.com/


If you want to source ...
        #1 Pharmaceutical raw material,
        #2 Oncology drug APIs,
        #3 Antibiotics or fine chemicals, 
We are a reliable manufacturer and supplier in China.

NEWBIO would like to ...
        #1 We foucus on the high purity and high quality;
        #2 We provide the raw materials at a good price;
        #3 We have the best service and we are always there for you.
Please contact us for more infomation!!!
Factory Direct Antibotic Dalbavancin with High Purity
(CAS: 171500-79-1)
 
=====================================
Chemical Information:
Quick Details: 
Product name Dalbavancin
CAS NO. 171500-79-1
Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Standard purity:>99%
Appearance Dalbavancin powder
Shelf life 2 years
Usage Dalbavancin is a novel second-generation lipoglycopeptide antibiotic.
Storage Dalbavancin should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

Product Name: Dalbavancin
Model No.: CYN-271
CAS No.: 171500-79-1
Molecular Formula: C88h100cl2n10o28
Molecular Weight: 1816.69
Appearance: White Crystalline powder
Melting Point: N/A
COA: Available
MSDS: Available
Spectrum: Available
Purity: 99%+
Suitable People: ALL People
Product Specifications: Pharmaceutical Grade 
Standard: Qualified
MOQ(Minimum Order Quantity): 10g
Payment: L/C, T/T, Western Union
Shipment: EMS, DHL, FedEx
Packing: Aluminium Foil Bag or as Required    

 
=====================================
Product Description:
Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).
Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.
Puhopharma specializes in controling the quality and reducing the impurities of Dalbavancin.
Our Dalbavancin is with the best quality and the most competitive price in China.
Dalbavancin (INN, trade names Dalvance in the US and Xydalba in Europe) is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).
Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.
It possesses in vitro activity against a variety of Gram-positive pathogens including MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE).
It is a once-weekly, two-dose antibiotic, the rights to which Actavis acquired when it bought Durata Therapeutics in 2014.
The Food and Drug Administration approved dalbavancin in May 2014 for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by certain susceptible bacteria such as Staphylococcus aureus including methicillin-susceptible and methicillin-resistant strains of Streptococcus pyogenes, in intravenous dosage form.
 
===================================== 
Applications/Usage:
Dalbavancin is an antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) in adults caused by susceptible Gram-positive organisms, including methicillin-resistant Staphylococcus aureus(MRSA).
It has strong activity against many Gram-positive bacteria, including methicillin-sensitive and methicillin-resistant Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus anginosus,Streptococcus intermedius, and Streptococcus constellatus.
Dalbavancin is a semi-synthetic glycopeptide prepared from A40926 by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram positive and multi-drug resistant isolates such as MRSA and MRSE.
 
===================================== 
Drug Interaction:
Clinical drug-drug interactions with dalbavancin have not been studied, and dalbavancin does not appear to interact with cytochrome P450 substrates, inhibitors, or inducers. It was found to have an in vitro synergistic interaction with the antimicrobial oxacillin, but the clinical significance of this interaction has yet to be established.
 
===================================== 
Mechanism of Action:
Dalbavancin is a lipoglycopeptide belonging in the same glycopeptide class. Similar to other glycopeptides, dalbavancin exerts its bactericidal effect by disrupting cell wall biosynthesis. It binds to the D-alanyl-D-alanyl residue on growing peptidoglycan chains and prevents transpeptidation from occurring, preventing peptidoglycan elongation and cell wall formation. Dalbavancin also dimerizes and anchors itself in the lipophilic bacterial membrane, thereby increasing its stability in the target environment and its affinity for peptidoglycan.
Antimicrobial activity correlates with the ratio of area under the concentration-time curve to minimum inhibitory concentration for Staphylococcus aureus.
 
===================================== 
Side Effects:
The most common adverse reactions encountered in Phase II and Phase III trials were nausea (5.5%), headache (4.7%), and diarrhea (4.4%), as well as rash (2.7%) and itchiness (2.1%).

===================================== 
COA:
Items Standard
Description White or almost white, crystalline powder
Water ≤0.5%
Residue on ignition ≤0.1
Limit of chloride NMT0.03%
Heavy metals NMT0.001%
Methanol NMT0.1%
Alcohol NMT0.1%
Related components A NMT0.5%
Any unknown impurity NMT0.10%
Total impurities NMT2.0%
Assay 98.0%~102.0%


FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
S# CAS No. Product Name S# CAS No. Product Name
1  86639-52-3 7-Ethyl-10-Hydroxycamptothecin 25  183321-74-6 Erlotinib
2  154229-18-2 Abiraterone Acetate 26  183319-69-9 Erlotinib Hydrochloride
3  50-76-0 Actinomycin D 27  159351-69-6 Everolimus
4  106941-25-7 Adefovir 28  56296-78-7 Fluoxetine Hydrochloride
5  850140-72-6 Afatinib 29  184475-55-6 Gefitinib Hydrochloride
6  330784-47-9 Avanafil 30  136572-09-3 Irinotecan Hydrochloride 
TriHydrate
7  319460-85-0 Axitinib 31  1441674-54-9 Ledipasvir(Acetone)
8  1421373-66-1 AZD-9291 (Mesylate) 32  191732-72-6 Lenalidomide
9  123524-52-7 Azelnidipine 33  21672  Methotrexate
10  863031-21-4 Azilsartan Medoxomil 34  76144-81-5 Mildronate
11  179324-69-7 Bortezomib 35  474645-27-7 Monomethyl Auristatin E
12  357336-20-0 Brivaracetam 36  63121-00-6 Oxaliplatin
13  842133-18-0 Canagliflozin 49  33069-62-4 Paclitaxel
14  928672-86-0 Canagliflozin HemiHydrate 37  137281-23-3 Pemetrexed Disodium
15  41575-94-4 Carboplatin 38  53123-88-9 Rapamycin
16  50935-04-1 Carubicin 50  135062-02-1 Repaglinide
17  288383-20-0 Cediranib 39  945667-22-1 Saxagliptin Hydrate
18  15663-27-1 Cisplatin 40  709031-78-7 Saxagliptin Hydrochloride
19  877399-52-5 Crizotinib 41  486460-32-6 Sitagliptin
20  171500-79-1 Dalbavancin 42  654671-77-9 Sitagliptin Phosphate Hydrate
21  114977-28-5 Docetaxel 44  85622-93-1 Temozolomide
22  148408-66-6 Docetaxel TriHydrate 45  477600-75-2 Tofacitinib
23  25316-40-9 Doxorubicin hydrochloride 46  540737-29-9 Tofacitinib Citrate
24  133040-01-4 Eprosartan 47  170791-09-0 Trityl Candesartan Cilexetil

ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment. 
#2 Secure and discreet shipment. 
#3 Various methods for your choice, like DHL/FedEx/SF-express.

OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3  We have QA&QC department to guarantees the quality, product pass rate can reach 100%. 

CONTACT US:
Telephone +86-027-87002705
Mobile +86-13277093700
Skype newbiopharmtech
FaceBook Page https://www.facebook.com/newbiopharma/
Facebook Group https://www.facebook.com/groups/1739616069613416/
Website http://www.newbiopharm.com/
Online Store http://biocar.en.made-in-china.com/


If you want to source ...
        #1 Pharmaceutical raw material,
        #2 Oncology drug APIs,
        #3 Antibiotics or fine chemicals, 
We are a reliable manufacturer and supplier in China.

NEWBIO would like to ...
        #1 We foucus on the high purity and high quality;
        #2 We provide the raw materials at a good price;
        #3 We have the best service and we are always there for you.
Please contact us for more infomation!!!