High Purity Masitinib Ab-1010 for Scientific Research

October 30, 2018

Model NO.: 790299-79-5
Trademark: Shuou
Transport Package: 25kg/Drum
Specification: 25kg/drum
Origin: China
HS Code: 3802900010
Model NO.: 790299-79-5
Trademark: Shuou
Transport Package: 25kg/Drum
Specification: 25kg/drum
Origin: China
HS Code: 3802900010
Masitinib Product Name: Masitinib (AB1010)
Masitinib Synonyms: MASITINIB; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; 4-((4-Methylpiperazin-1-yl)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)-1, 3-thiazol-2-yl)amino)phenyl)benzamide; Ab 1010; Ab1010; Ab-1010; Mastinib; Masitinib(AB1010)
Masitinib CAS: 790299-79-5
Masitinib MF: C28H30N6OS
Masitinib MW: 498.64
Masitinib EINECS: 
Masitinib Product Categories: Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; Anti-cancer&immunity; Inhibitors
Masitinib Mol File: 790299-79-5. mol

Feature Masitinib has a better safety than other tyrosine inhibitors. 
Chemical Properties Off-White to Pale Yellow Solid
Masitinib Usage Masitinib is a novel tyrosine kinases inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, resectively. 
Masitinib Usage Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 2/3
Masitinib Usage Masitinib controlled-release implant for treating solid neoplasm. 

Masitinib Description

Masitinib is a potent and selective tyrosine kinase inhibitor targeting KIT that is active, orally bioavailable in vivo, and has low toxicity. Phase II clinical trials demonstrate that Masitinib appears to be effective as a first-line treatment of advanced GIST with comparable results to imatinib in terms of safety and response. PFS and in particular OS data show promise that masitinib may provide sustainable benefits. 
Masitinib, also known as methotrexate masitinib, is studied and developed by the AB Science, a platelet-derived growth factor alpha/beta receptor tyrosine kinase inhibitor for the treatment of multiple myeloma, gastrointestinal stromal tumors and prostate cancer. 

The drug had respectively, been entitled by FDA for the treatment of pancreatic cancer and ALS orphans disease in 2009 and 2015. On August 8, 2016, it has qualified as EMA orphan drug. 

Our Advantage
 
Best Quality Professional leading manufacturers in China.Strict
quality control before products are allowed to sell.
Competitive Price Factory direct sales.Best prices you're sure to be
satisfied.
Safe Packing Professional packing department which have more
than 16 years experience in disguising packages
Fast Delivery Plenty in stock,delivery within 24 hours after the
payment.Fast and secure delivery by DHL, TNT,
FedEx, HKEMS, UPS, etc.
Payment T/T,Western Union,Money Gram,Bitcoin.
Service Photos of parcel and tracking number offered
timely;24/7 online helpful service
Discount Specials are possible when client's order is big
enough, including the discount policy


Hot Product list

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High Purity Masitinib Ab-1010 for Scientific Research

High Purity Masitinib Ab-1010 for Scientific Research
High Purity Masitinib Ab-1010 for Scientific Research

Masitinib Product Name: Masitinib (AB1010)
Masitinib Synonyms: MASITINIB; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; 4-((4-Methylpiperazin-1-yl)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)-1, 3-thiazol-2-yl)amino)phenyl)benzamide; Ab 1010; Ab1010; Ab-1010; Mastinib; Masitinib(AB1010)
Masitinib CAS: 790299-79-5
Masitinib MF: C28H30N6OS
Masitinib MW: 498.64
Masitinib EINECS: 
Masitinib Product Categories: Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; Anti-cancer&immunity; Inhibitors
Masitinib Mol File: 790299-79-5. mol

Feature Masitinib has a better safety than other tyrosine inhibitors. 
Chemical Properties Off-White to Pale Yellow Solid
Masitinib Usage Masitinib is a novel tyrosine kinases inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, resectively. 
Masitinib Usage Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 2/3
Masitinib Usage Masitinib controlled-release implant for treating solid neoplasm. 

Masitinib Description

Masitinib is a potent and selective tyrosine kinase inhibitor targeting KIT that is active, orally bioavailable in vivo, and has low toxicity. Phase II clinical trials demonstrate that Masitinib appears to be effective as a first-line treatment of advanced GIST with comparable results to imatinib in terms of safety and response. PFS and in particular OS data show promise that masitinib may provide sustainable benefits. 
Masitinib, also known as methotrexate masitinib, is studied and developed by the AB Science, a platelet-derived growth factor alpha/beta receptor tyrosine kinase inhibitor for the treatment of multiple myeloma, gastrointestinal stromal tumors and prostate cancer. 

The drug had respectively, been entitled by FDA for the treatment of pancreatic cancer and ALS orphans disease in 2009 and 2015. On August 8, 2016, it has qualified as EMA orphan drug. 

Our Advantage
 
Best Quality Professional leading manufacturers in China.Strict
quality control before products are allowed to sell.
Competitive Price Factory direct sales.Best prices you're sure to be
satisfied.
Safe Packing Professional packing department which have more
than 16 years experience in disguising packages
Fast Delivery Plenty in stock,delivery within 24 hours after the
payment.Fast and secure delivery by DHL, TNT,
FedEx, HKEMS, UPS, etc.
Payment T/T,Western Union,Money Gram,Bitcoin.
Service Photos of parcel and tracking number offered
timely;24/7 online helpful service
Discount Specials are possible when client's order is big
enough, including the discount policy


Hot Product list

Sertraline Hydrochloride CAS 79559-97-0
Piracetam     CAS  7491-74-9
Tianeptine Sodium CAS  30123-17-2
Paroxetine hydrochloride  CAS 78246-49-8
Adrafinils  CAS 63547-13-7 
Phenibut CAS 1078-21-3
Trazodone HCl  CAS 25332-39-2
Venlafaxine HCl    CAS 99300-78-4
Duloxetine HCl  CAS 136434-34-9
Mirtazapine(Remeron) CAS 61337-67-5
Paroxetine Hydrochloride CAS 78246-49-8
Vortioxetine CAS 508233-74-7
Vortioxetine Hydrobromide  CAS 960203-27-4
5-Hydroxytryptophan CAS 56-69-9
Fluoxetine Hydrochloride  CAS 56296-78-7
Tianeptine Free Acid CAS 66981-73-5
Carisoprodol CAS 78-44-4
Hydroxyzine Dihydrochloride CAS 2192-20-3
Citalopram Hydrobromide CAS 59729-32-7
Agomelatine CAS 138112-76-2
Escitalopram oxalate CAS 219861-08-2
Amitriptyline HCL CAS 549-18-8
Clomipramine hydrochloride CAS 17321-77-6
Doxepin HCL CAS 1229-29-4
Duloxetine CAS 116539-59-4
Tandospirone CAS 87760-53-0
Tianeptine Sulphate  CAS 1224690-84-9

High Purity Masitinib Ab-1010 for Scientific Research

High Purity Masitinib Ab-1010 for Scientific Research
High Purity Masitinib Ab-1010 for Scientific Research