Product Name:Cabozantinib Malate
CAS: 1140909-48-3
MF: C32H30FN3O10
MW: 635.5931032
Product Categories: Inhibitors
Chemical Properties: Off-White Solid
Grade Standard:Medicine Grade
Usage:For the treatment of advanced, metastatic thyroid medullary carcinoma (MTC) patients
Description
Cabozantinib (marketed under the tradename Cometriq, formerly known as XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM. XL-184 also displays potent activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2, and AXL. XL184 at low concentration(0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion.
Functions of Cabozantinib Malate
Cabozantinib is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and has been shown to reduce tumor growth, metastasis, and angiogenesis.
Cabozantinib is approved for medullary thyroid cancer. and advanced renal cell carcinoma in people who have received prior anti-angiogenic therapy. It is currently undergoing clinical trials for the treatment of prostate, bladder, ovarian, brain, melanoma, breast, non-small cell lung, pancreatic, and hepatocellular cancers. Â
Cabozantinib Malate Usage And Synthesis
Our factory& workshop
 Commerce Clause
Minimum Order Quantity:
100gram
Price:
Negotiable
Payment Terms:
Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin
Packaging Details:
Discreet and Disguised packing
Delivery time:
Within 12 hours after receiving the payment
Leading time:
4~6 working days after confirming the payment
Delivery
By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable
Tracking number
can be offered to you within 24h
Supply Ability:
Mass in stock
 
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Inhibitors Cabozantinib Malate CAS1140909-48-3 for advanced MTC
Product Name:Cabozantinib Malate
CAS: 1140909-48-3
MF: C32H30FN3O10
MW: 635.5931032
Product Categories: Inhibitors
Chemical Properties: Off-White Solid
Grade Standard:Medicine Grade
Usage:For the treatment of advanced, metastatic thyroid medullary carcinoma (MTC) patients
Description
Cabozantinib (marketed under the tradename Cometriq, formerly known as XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM. XL-184 also displays potent activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2, and AXL. XL184 at low concentration(0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion.
Functions of Cabozantinib Malate
Cabozantinib is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and has been shown to reduce tumor growth, metastasis, and angiogenesis.
Cabozantinib is approved for medullary thyroid cancer. and advanced renal cell carcinoma in people who have received prior anti-angiogenic therapy. It is currently undergoing clinical trials for the treatment of prostate, bladder, ovarian, brain, melanoma, breast, non-small cell lung, pancreatic, and hepatocellular cancers. Â
Cabozantinib Malate Usage And Synthesis
Our factory& workshop
 Commerce Clause
Minimum Order Quantity:
100gram
Price:
Negotiable
Payment Terms:
Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin
Packaging Details:
Discreet and Disguised packing
Delivery time:
Within 12 hours after receiving the payment
Leading time:
4~6 working days after confirming the payment
Delivery
By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable
Tracking number
can be offered to you within 24h
Supply Ability:
Mass in stock
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s
Inhibitors Cabozantinib Malate CAS1140909-48-3 for Advanced Mtc
Model NO.: 1140909-48-3
CAS: 98319-26-7
Shipping Time: 1 Day for Ready Goods
Delivery: 3-5 Business Days
Customs Success Rate: >99%
Shipping Method: DHL, FedEx, TNT, Hkems, EMS Express
Supply Ability: Mess in Stock
Mf: C27h30clno11
Payment: T/T, Western Union, Money Gram, Paypal, Bitcoin
MOQ: 10g
Guarantee: Support Resending Police
Trademark: Pharmcy
Transport Package: Customized
Specification: ISO9001
Origin: China
HS Code: 846321864
Model NO.: 1140909-48-3
CAS: 98319-26-7
Shipping Time: 1 Day for Ready Goods
Delivery: 3-5 Business Days
Customs Success Rate: >99%
Shipping Method: DHL, FedEx, TNT, Hkems, EMS Express
Supply Ability: Mess in Stock
Mf: C27h30clno11
Payment: T/T, Western Union, Money Gram, Paypal, Bitcoin
MOQ: 10g
Guarantee: Support Resending Police
Trademark: Pharmcy
Transport Package: Customized
Specification: ISO9001
Origin: China
HS Code: 846321864
Inhibitors Cabozantinib Malate CAS1140909-48-3 for advanced MTC